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It is an intracellular metabolic-enzyme modulator, which is why its research read-outs are things like NAD+ levels and adipocyte gene expression, not “how full you feel.” That mechanistic distinction is the single most important thing to understand before looking at any dose number

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10.1038/s41580-020-0230-3 [DOI] [PubMed] [Google Scholar] Silva-Adaya D., Gonsebatt M